Global burden and genetic pathways of knee osteoarthritis: An integrated analysis of GBD data, Mendelian randomization, and multi-omics approaches.

Medicine (Baltimore) · 2026 · PMC13095278 · PMID 41995561

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an increasing trendno p-value reported

Global KOA incidence showed an increasing trend, consistent with Jia-Le Ren et al’s findings, [ 28 ] peaking at 47.5 years with a higher risk before age 62.5.

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