Integrating bulk, single-cell, and spatial transcriptomics to identify a novel pyroptosis-related gene signature for predicting prognosis and tumor immune landscape in triple-negative breast cancer.

Front Immunol · 2026 · PMC13095739 · PMID 42023218

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP< 0.001actually significant

As shown in Supplementary Figure S7 , the risk score remained a highly significant and independent prognostic factor (HR = 7.183, 95% CI: 2.852–18.092, P< 0.001) even after adjusting for overall immune infiltration intensity.

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borderline significanceno p-value reported

PFKFB3 and TREM1 showed borderline significance after adjustment.

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