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<b>Broadly cross-reactive mRNA COVID-19 vaccine encoding trimeric RBDs and NSP12 mitigates immune imprinting</b>.

Mol Ther Nucleic Acids · 2026 · PMC13096956 · PMID 42023032

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a slight trendno p-value reported
Total IgG titers at 4 weeks post-immunization were also similar between the monomeric and trimeric groups, although a slight trend toward higher titers was observed with the trimeric construct ( Figure 2 C).

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