The association between modified cardiometabolic index and cardiovascular disease risk in adults with early cardiovascular-kidney-metabolic syndrome: a prospective cohort study.

BMC Cardiovasc Disord · 2026 · PMC13097706 · PMID 41820977

Europe PMC DOI

hedged sentences

0.0080

closest p · 0.2× alpha

0.0080

boldest claim

The sentences

borderline significantp = 0.008actually significant

Notably, the highest MCMI quartile still showed borderline significant heart disease risk in Model 3 (HR = 1.29, p = 0.008), implying MCMI captures unique metabolic dysregulation patterns/synergistic effects not fully reflected by individual traditional indicators.

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highly significantno p-value reported

The overall association was highly significant ( P -overall < 0.001), displaying a J-shaped curve where risk accelerated more rapidly beyond certain MCMI thresholds.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.