Targeting the FGF19/FGFR4 positive feedback loop to disrupt ERK-mediated tumor progression in head and neck cancer.

J Transl Med · 2026 · PMC13097793 · PMID 41821016

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

borderline significanceP = 5.4 × 10 − 2so close (0.05 < p ≤ 0.1)

In univariate Cox analysis, FGFR4 expression was significantly associated with poor overall survival ( P = 4.8 × 10 − 2 ), with borderline significance in multivariate analysis after adjustment for T and N classifications ( P = 5.4 × 10 − 2 ; Table S3 ).

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