The greater the pleiotropic effects, the greater the benefits - cannabis as a "biopsychosocial" drug: a mixed-methods study on chronic non-cancer pain.

J Cannabis Res · 2026 · PMC13097855 · PMID 42015327

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highly significantno p-value reported

2022 ), which examined long-term observational studies on CBM (mainly by inhalation) and included data from around 2,500 patients, showed highly significant improvements not only in terms of pain intensity, but also in terms of function, sleep quality, depression, anxiety and general QOL.

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