Barely Significant
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Bridging FDA Adverse Event Reporting System (FAERS) and Clinical Practice: Comprehensive Characterization of Immune Checkpoint Inhibitors Toxicities in Geriatric Lung Cancer Patients.

Thorac Cancer · 2026 · PMC13098177 · PMID 41825930

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a nonsignificant trendno p-value reported
A nonsignificant trend was observed wherein ICI‐related hypothyroidism was more common in the 65–75 years group, while ICI‐related arthritis was more frequent in the > 75 years group. 4 Discussion ICI‐associated AEs significantly complicate cancer immunotherapy, particularly in geriatric patients who face increased risks due to age‐related immune senescence [ 12 , 13 , 14 , 15 ].

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