QcrB inhibitor Q203 (Telacebec) can synergize with clofazimine and clarithromycin to control a Mycobacterium avium infection.

PLoS One · 2026 · PMC13098918 · PMID 42013119

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highly significantno p-value reported

The addition of 5 mg/kg of Q203 to the CLR + CFZ resulted in a highly significant decrease in lung CFU, with a 1.5 log drop relative to CLR + CFZ and 2.7 log drop compared to vehicle control ( Fig 2A and S2 Table ).

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