A randomized prospective study comparing intracuff dexmedetomidine and alkalinized lidocaine for the prevention of postoperative sore throat, hoarseness, and cough in prolonged prone-position spine surgery.

Saudi J Anaesth · 2026 · PMC13099049 · PMID 42022095

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highly significantno p-value reported

A P <0.05 was considered statistically significant; P < 0.001 was considered highly significant.

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a slight trendno p-value reported

No statistically significant differences were found in POST incidence, hoarseness, pain scores, or hemodynamic measures, though dexmedetomidine showed a slight trend toward better symptom prevention.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.