Human Primary Mesenchymal Stem Cells Fail to Recover Full Osteogenic Differentiation Potential Following Washout of Electronic Cigarette Aerosol Extracts.

Nicotine Tob Res · 2026 · PMC13102001 · PMID 41247321

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highly significantp < .0001actually significant

Compared to control cells, MSCs exposed continuously to either cigarette or e-cigarette smoke aerosol extracts exhibited a highly significant inhibition of cell viability, with 30% and <60% of MSCs surviving the 2-week cigarette and e-cigarette smoke aerosol extract exposure ( p < .0001), respectively.

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