Barely Significant
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Fibrin sealant for prophylaxis of cervical anastomotic leakage after McKeown esophagectomy for esophageal or esophagogastric junction cancer (PLACE030): a Phase III multicenter randomized clinical trial.

Int J Surg · 2026 · PMC13105525 · PMID 41677267

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a nonsignificant trendno p-value reported
According to the subgroup analysis, patients who underwent upfront surgery showed a nonsignificant trend toward better outcomes with the application of FS (Fig. 3 ).

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