Rather than merely validating computational affinities, the massive surge in ROS and the highly significant upregulation of active cleaved-Caspase-3 observed in DOTP-exposed murine cortices provide a definitive biochemical basis for the severe neuronal pyknosis and cytoarchitectural disruption seen in our histological evaluations.
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Effective analysis of neurotoxicity and mechanisms of dioctyl terephthalate using network toxicology.
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