Single versus repeated intravenous oncolytic reovirus infusions: Implications for immune modulation and rationalised scheduling of therapy in hepatocellular carcinoma.

45 , 46 Our HCC in vivo model demonstrates a highly significant transient elevation in PD‐L1 expression on both CD4+ and CD8+ T‐cells from tumours, livers and dLNs in response to a single reovirus injection, peaking at d3 then reducing at later time points.

also in 132,142 other papers