highly significantp < 0.0001
Statistical modelling of FICI values The results of the Wald χ 2 tests from the fitted linear mixed-effects model evaluating FICI values indicated that antibacterial combination had a strong and highly significant main effect on FICI values ( p < 0.0001), as did compound ratio ( p < 0.0001), indicating that both the identity of the combination and the dosage ratio influenced the degree of synergism.