Early methylprednisolone pulses and prevention of long-term damage accrual in active systemic lupus erythematosus: a propensity score analysis of the Lupus-Cruces-Bordeaux cohort.

RMD Open · 2026 · PMC13110706 · PMID 42031508

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marginally significantp=0.08so close (0.05 < p ≤ 0.1)

Analysis by subcategories of damage in the whole cohort A significant global reduction in the risk for accruing lupus-related damage was seen among MP users (adjusted HR 0.28, 95% CI 0.09 to 0.82, p=0.02), with a marginally significant risk reduction of GC-related damage (adjusted HR 0.37, 95% CI 0.12 to 1.13, p=0.08).

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