Preliminary insights into gut microbiome shifts as screening proxy for MASLD disease progression.

Epidemiological data estimate global prevalence values around 24–30% with an increasing trend in parallel with obesity and metabolic syndrome 88 making MASLD as the second cause of liver transplantation in westernised countries 89 .

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prausnitzii values evidenced a decreasing trend with respect to patient groups according to clinical severity (ranging from 1.4 × 10 9 to 3.6 × 10 10 , median values; Fig. 1 ).

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