In the SIC cohort, the INR linear term was non-significant ( p = 0.186), the quadratic term approached but did not reach significance ( p = 0.067), and only the spline model captured the predictive signal (ΔAUROC + 0.021).
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Prognostic Value of International Normalized Ratio and Thrombocytopenia in Early Risk Stratification of Septic Patients.
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0.0670
0.0670