Antibiotic-Loaded PLA Composites for Local Prevention of Implant-Associated Infections: Comparative Evaluation Against Reference Strains and Clinical Isolates.

Antibiotics (Basel) · 2026 · PMC13113662 · PMID 42041336

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borderline significanceno p-value reported

Differences between PLA–ciprofloxacin and PLA–gentamicin were statistically significant for Gram-negative pathogens, whereas for staphylococcal isolates they approached borderline significance after correction for multiple comparisons, indicating comparable activity profiles of these composites within the applied experimental model.

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