Caloric Restriction Mimetic Hydroxycitrate Mitigates Acute Nephrotoxicity via Autophagy Activation and Oxidative Stress Reduction.

The level of PCNA, a marker for cell proliferation, after 3 or 7 weeks of HC treatment showed no significant differences between treated and untreated groups, although it possessed a decreasing trend in AKI-induced PCNA in the “7-w HC + GM” group compared to “GM” group ( Figure 4 F and Figure 5 F, correspondingly). 3.5.

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