A Matrix-Free 3D Hepatocyte-Macrophage Co-Culture Spheroid Model for Dual Assessment of Lipid Accumulation and NF-κB-Mediated Inflammatory Activation Under Glucolipotoxic Stress.

Biomedicines · 2026 · PMC13114099 · PMID 42072333

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an increasing trendno p-value reported

Dose-dependent separation was most evident for NF-κB activity under high-glucose conditions, whereas lipid accumulation in LG showed higher variability despite an increasing trend.

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