Integrated Analysis of Cerebral Small Vessel Disease and Facial Soft-Tissue Markers in the Alzheimer's Disease Continuum.

Brain Sci · 2026 · PMC13115214 · PMID 42041811

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0520

boldest claim

The sentences

highly significantp < 0.0001actually significant

Results: The AD group showed a highly significant cognitive decline (MMSE: 23.2 ± 4.1 vs. 28.2 ± 1.4, p < 0.0001).

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borderline significantp = 0.052so close (0.05 < p ≤ 0.1)

It is also noteworthy that the significance was more robust in the right masseter ( p = 0.023), while the left was borderline significant ( p = 0.052), providing support for a bilateral finding, albeit with asymmetry.

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