Analytical Models to Optimize Tacrolimus Dosing in Solid Organ Transplantation: A Systematic Review.

Pharmaceutics · 2026 · PMC13119010 · PMID 42076083

Europe PMC DOI

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might not be significantno p-value reported

Despite CYP3A5 expressors requiring 1.2–2.2 times higher doses [ 78 , 81 , 82 ], the clinical impact of genomic testing might not be significant beyond initial dosing [ 9 , 148 ].

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