Impact of Vitamin D3 Supplementation on 28-Day ICU Mortality in Sepsis Patients: A Retrospective Study with Propensity Score Matching.

Pathogens · 2026 · PMC13119377 · PMID 42075760

Europe PMC DOI

hedged sentence

0.0880

closest p · 1.8× alpha

0.0880

boldest claim

The sentences

borderline significantp = 0.088so close (0.05 < p ≤ 0.1)

In the stratification by baseline vitamin D level, vitamin D3 supplementation was associated with reduced mortality in both the normal vitamin D subgroup (HR = 0.14, 95% CI: 0.04–0.52, p = 0.003) and the deficient vitamin D subgroup (HR = 0.47, 95% CI: 0.21–0.96, p = 0.047), with a borderline significant interaction between the two groups ( p = 0.088).

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