Barely Significant
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Immune-focused RBD nanoparticles induce cross-reactive, RBS-directed responses capable of variant-resistant SARS-CoV-2 neutralization.

PLoS Pathog · 2026 · PMC13120701 · PMID 41712614

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highly significantno p-value reported
The antigenic and immunologic impacts of these mutations on an immune focused ancestral RBD are highly significant.

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