an increasing trendP = 0.005
Building on these observations, our cohort showed an increasing trend in whole-liver uptake across fibrosis strata and a modest positive correlation with the FIB-4 score (r = 0.37 , P = 0.005), suggesting that the hepatic uptake pattern on [ 18 F]AlF-NOTA-FAPI-04 PET/CT is, to some extent, associated with the burden of fibrosis-related remodeling.