Barely Significant
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Direct Oral Anticoagulants Versus Warfarin in Atrial Fibrillation With Advanced Chronic Kidney Disease: A Systematic Review and Meta-Analysis.

Cureus · 2026 · PMC13121516 · PMID 42058359

Europe PMCDOI
1
hedged sentence
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

highly significantp < 0.0001actually significant
standard 5 mg versus reduced 2.5 mg twice daily) and differing proportions of dialysis-dependent versus non-dialysis advanced CKD patients across the included studies." Meta-regression confirmed that the specific DOAC agent was a highly significant moderator of bleeding risk (Q M = 22.88, p < 0.0001).

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