Mutations in CHIP-associated genes at myeloid neoplasm diagnosis and risk of cardiovascular/cerebrovascular events.

Ann Med · 2026 · PMC13123072 · PMID 42037246

Europe PMC DOI

hedged sentence

0.0850

closest p · 1.7× alpha

0.0850

boldest claim

The sentences

a nonsignificant trendp =0.085so close (0.05 < p ≤ 0.1)

In joint age-mutation analyses, mutation-positive patients aged ≥70 years had the highest CCVE risk (aHR, 2.77; 95% CI, 1.17–6.56), whereas younger mutation-positive patients showed a nonsignificant trend (aHR, 2.16; 95% CI, 0.90–5.20; p =0.085); interaction was not significant ( p =0.29).

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