The microbiota-gut-brain axis perspective: mechanisms and intervention strategies for the comorbidity of chronic constipation and depression.

Front Microbiol · 2026 · PMC13124977 · PMID 42063504

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an increasing trendno p-value reported

Depression is one of the most common psychiatric disorders and has a global prevalence of approximately 4.4% and demonstrates an increasing trend ( GBD 2019 Mental Disorders Collaborators, 2022 ).

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