Salivary microbial meta-analysis reveals gender differences in oral microbiota, core microbiota, and molecular markers.

Front Cell Infect Microbiol · 2026 · PMC13125147 · PMID 42064213

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At the same time, 37.84% of the OSCC group were classified as Pre-OSCC, which may indicate that as a precursor lesion of OSCC, the microbial composition of pre-OSCC and OSCC has a certain similarity, and there may be significant changes in the salivary microbial composition in the early stage of the whole process which affects the development of the disease ( Lin et al., 2021 ).

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