Fecal melatonin as a biomarker of emerging circadian maturity and gut microbiota in infancy.

NPJ Biol Timing Sleep · 2026 · PMC13125696 · PMID 42050171

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a weak trendno p-value reported

However, at 6 and 12 months, sleep onset latency exhibited a weak trend-level relationship with fecal melatonin, though this did not withstand FDR correction.

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marginally significantno p-value reported

The results showed a positive association between fecal melatonin and sleep onset latency (coef = 0.1096, p = 0.02, std= 0.05), which remained marginally significant after multiple comparison adjustment (FDR = 0.053).

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