After 1 week of intervention with different concentrations of JNJ0966, serum MMP-9 levels were significantly lower in the SHR-C-30 group than in the SHR-C-0 group ( P = 0.0280), while the MMP-9/TIMP-1 ratio exhibited a decreasing trend.
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The JNJ0966 Significantly Reduces the Elevated Serum MMP-9 and Blood Pressure Observed in SHRs With Periodontitis.
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