Primary Debulking Surgery Versus Neoadjuvant Chemotherapy in Advanced Ovarian Cancer: A Meta-Analysis of All Randomized Clinical Trials with Subgroup Analysis by Patient Profile.

Oncol Res · 2026 · PMC13126584 · PMID 42065038

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a slight trendno p-value reported

When focusing on highly selected subgroups, such as patients with disease confined to the abdomen, those younger than 70 years, or those who achieved complete cytoreduction, no statistically significant survival advantage emerged for PDS, although a slight trend toward improved outcomes was observed.

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