Complement Components C1r and C8 Serve as Potential Inflammatory Biomarkers for Coronary Heart Disease Severity: The Mediating Role of C-Reactive Protein.

Compared to the mild coronary artery stenosis group (Gensini≤31), the moderate-to-severe coronary artery stenosis group (Gensini>31) had significantly higher proportions of males and individuals with a history of smoking, with statistically significant differences (P < 0.05).Laboratory tests revealed that in the Gensini >31 group, WBC, NE, CRP, Scr, UA, LDH, cTnT, and NT-proBNP levels were significantly higher compared to the Gensini ≤31 group (all P < 0.05).Regarding echocardiographic parameters, the Gensini >31 group showed an increasing trend in LVEDD and a decreasing trend in LVEF, with both differences being statistically significant (P < 0.05).

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