Monoclonal Antibodies Accessing the Cytosol of Living Cells and Binding to Polo-Like Kinase 1 Interdomain Linker Affect Mitotic Behavior.

Chembiochem · 2026 · PMC13127698 · PMID 42054108

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highly significantno p-value reported

Nontreated cells, cells electroporated with Luciferase siRNA, and cells containing anti‐NuPore mAbs completed mitosis in ≈50 min, whereas anti‐PLK1 3F8‐containing cells exhibited a prolonged ANOVA statistical analysis indicated that these differences were highly significant ( q ‐value of 10 −16 comparing the anti‐PLK1 condition to the anti‐NuPore one).

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