Molecular Stratification of Antiphospholipid Syndrome Through Integrative Analysis of the Whole-Blood RNA Transcriptome.

Arthritis Rheumatol · 2026 · PMC13129634 · PMID 41399015

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP = 3.86 × 10 −41actually significant

Both the NET formation and Hippo/IL‐6 signaling gene modules remained highly significantly associated with cluster 4 after these adjustments (NET formation: adjusted cluster P = 3.86 × 10 −41 ; Hippo/IL‐6 signaling: adjusted cluster P = 4.98 × 10 −24 ), and the results were unchanged even after excluding all patients receiving HCQ or any immunosuppressive therapy.

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