a nonsignificant trendP = 0.075
Although rheumatoid arthritis exhibited only a nonsignificant trend toward higher prevalence (odds ratio (OR) = 1.81; P = 0.075), and multiple sclerosis did not show a significant association (OR = 0.90; P = 0.07), the overall pattern indicates a systemic predisposition to immune dysregulation among women with PCOS ( Sharmeen et al. 2021 , Jiang et al. 2024 ).