mPFC Synaptosome Proteomics Reveals Novel Pathways and Muscarinic Receptor Changes in a Learned Helplessness Mouse Model.

eNeuro · 2026 · PMC13131696 · PMID 41980822

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failed to reach significanceno p-value reported

The “Clathrin-mediated endocytosis” pathway, which is involved in muscarinic receptor internalization ( Fryer et al., 2012 ), also showed increased activity in females but failed to reach significance in males.

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