Impact of Vaginal Estradiol on the Genitourinary Syndrome of Menopause, Vaginal Microbiome and Mucosal Immune Mediators in Women With HIV.

Clin Infect Dis · 2026 · PMC13131915 · PMID 41355723

Europe PMC DOI

hedged sentence

0.1300

closest p · 2.6× alpha

0.1300

boldest claim

The sentences

a nonsignificant trendP = .13not close (p > 0.1)

VMI Improved in the Estradiol Treatment Group There was a nonsignificant trend toward improvement in the clinical vaginal atrophy score in the estradiol group ( P = .13) but no change in the no treatment group between baseline and 12-week ( Figure 2 B ).

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