This conclusion was further supported by the eigengene (first principal component of the 20 gene-set expression matrix) analysis plot (Welch’s t-test: t = −14.12, p = 6.52e-26) ( Fig 6C ), indicating highly significant variations in biomarker activity in rejection samples.
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Integrated cross-organ transcriptomic analysis uncovers conserved gene signatures predictive of allograft rejection.
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