A causal glycerophospholipid-IL-18R1-CD9 axis connects lipid metabolism and T-cell activation in atopic dermatitis.

Brief Bioinform · 2026 · PMC13132603 · PMID 42061907

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

highly significantP = 1.92 × 10 −4actually significant

The results were conclusive: only IL-18R1 maintained a highly significant direct causal effect on AD (β = 0.023, P = 1.92 × 10 −4 ), whereas the direct effects of both PA-GPC ( P = .074) and IL-18 ( P = .084) became non-significant.

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