Thalamic dynamics orchestrate the recovery of tonic alertness during nocturnal sleep inertia.

Of note, the mediation model of thalamus activation mediating the relationship between length of NREM 2&3 sleep and PVT median speed was marginally significant (indirect effect estimate=059, p = 0.067); and the significant path c in this model (Table S5 ) suggested a negative direct effect without introducing the mediator (estimate = −0.008, p = 0.03).

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In contrast, the PW group showed a decreasing trend in post-sleep PVT performance (Fig.

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