Piezoelectric neuromodulation of the subthalamic nucleus ameliorates motor and nonmotor symptoms of Parkinson's disease.

Compared with the PDA@BT NP group, the expression level of TH in the PDA@BT NP + US group cells showed an increasing trend ( Fig. 3E ). c-Fos + , as a kind of immediate early gene, is rapidly expressed when neurons are stimulated or activated, and the nucleoprotein c-Fos + encoded by it is enriched and expressed in neurons.

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