Integrative Metabolomic, Network Pharmacology, and Experimental Evidence for <i>Lepidium sativum</i> Seed Extract as a Natural Modulator of Pulmonary Fibrosis via the <i>ncNRFR/Let-7d</i> Regulatory Pathway.

Pharmaceuticals (Basel) · 2025 · PMC13134761 · PMID 41471309

Europe PMC DOI

hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp < 0.0001actually significant

Beginning at doses >50 mg/kg, CSE reduced TGF-β levels toward those of the control group, while simultaneously restoring E-cadherin expression, with highly significant increases at 100 and 150 mg/kg ( p < 0.0001).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Integrative Metabolomic, Network Pharmacology, and Experimental Evidence for &lt;i&gt;Lepidium sativum&lt;/i&gt; Seed Extract as a Natural Modulator of Pulmonary Fibrosis via the &lt;i&gt;ncNRFR/Let-7d&lt;/i&gt; Regulatory Pathway.

The sentences

Integrative Metabolomic, Network Pharmacology, and Experimental Evidence for <i>Lepidium sativum</i> Seed Extract as a Natural Modulator of Pulmonary Fibrosis via the <i>ncNRFR/Let-7d</i> Regulatory Pathway.