Flexible regulation of CRISPR/Cas12a activity by spatial confinement effect.

Nucleic Acids Res · 2026 · PMC13136891 · PMID 42080258

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantP < 0.0001actually significant

5D , statistical analysis confirmed that CAS-FLIER effectively discriminated HIV patients from HC with highly significant differences ( P < 0.0001), which was consistent with qRT-PCR ( P < 0.0001).

also in 132,142 other papers

an increasing trendno p-value reported

1F , as the ratio increased gradually from 25:1 to 150:1, the fluorescence signal exhibited an increasing trend, accompanied by a concurrent gradual elevation of the background signal.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.