Acute anti-proliferative and anti-migratory effects of cannabidiol on C6 rat glioma, SH-SY5Y human neuroblastoma, and HT22 mouse hippocampal neuronal cell cultures.

Front Toxicol · 2026 · PMC13138797 · PMID 42088408

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highly significantp < 10 −10actually significant

Several proteins were upregulated in the CBD-treated group, including large ribosomal subunit proteins (uL30/Rpl7, uL1/Rpl10a, uL2/Rpl8), molecular chaperones (Hsp90b1, Hspe1, Hspd1), calumenin (Calu), and macrophage migration inhibitory factor (Mif), all with highly significant changes (p < 10 −10 , FDR <10 −9 ).

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