Identification and validation of a nomogram for psoriasis diagnosis: a novel biomarker combination with stable high expression in the early stage.

Front Med (Lausanne) · 2026 · PMC13138929 · PMID 42094951

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0800

boldest claim

The sentences

highly significantp < 0.001actually significant

Most notably, the candidate serum biomarkers (ORM1, ORM2, AGP) and the vast majority of systemic inflammation composite indices (NLR, MLR, SII, SIRI) showed a highly significant upward trend in the study group (all p < 0.001), suggesting that these indicators are more sensitive in reflecting systemic inflammation of psoriasis compared to conventional blood indicators. 3.2.

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close to being significantp = 0.080so close (0.05 < p ≤ 0.1)

ORM1 was slightly positively correlated with the risk, and the overall model was close to being significant ( p = 0.080), but there was no significant non-linear relationship.

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