Safety Assessment of Glucagon-Like Peptide 1 Receptor Agonists Based on the FAERS Database: Focus on Tumorigenic Risk in Subpopulations.

In body weight analysis, “decreased appetite” remained the most frequent signal, showing a positive trend with increasing weight, whereas other PTs showed minimal variation across weights.

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In the 18–30 age group, PT frequencies, from highest to lowest, included “nausea,” “vomiting,” “diarrhea,” “blood glucose increased,” “weight decreased,” “injection site pain,” “decreased appetite,” and “injection site hemorrhage.” As age increased, “nausea,” “vomiting,” and “diarrhea” showed a decreasing trend, whereas the other PTs increased, with “blood glucose increased” and “weight decreased” showing the most significant increase with age.

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