Barely Significant
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BABAPPAlign: a multiple sequence alignment engine with a learned residue-level scoring function.

Bioinformatics · 2026 · PMC13141150 · PMID 41992497

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highly significantno p-value reported
Replacing the learned scorer with BLOSUM62 within the same alignment engine caused large and highly significant drops in both SP and TC on BAliBASE, PREFAB, and HOMSTRAD-100.

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