GSC-associated cytokines (Wnt, IL-6, TGF-β, IL-1β, and CXCL12) also showed a decreasing trend following RNVTFe and RNVTFe-Tf treatment compared with PBS, TMZ, and RNVT groups ( Fig. 9 E–I).
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Fe<sup>3+</sup>-based nanovesicle mediated transferrin hijacking for glioblastoma stem cell tumoricidal treatment and postoperative recurrence inhibition.
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