Pre-treatment vitamin D insufficiency predicts severe paclitaxel-induced sensory neuropathy in breast cancer patients: a prospective cohort study.

Other risk factors Our analysis identified postmenopausal status as a potential risk factor for severe CIPN, with a trend toward significance in multivariate analysis (adjusted OR = 1.88, p = 0.075).

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In multifactorial conditions like CIPN, it is well-established that a biomarker can be a highly significant risk factor without possessing the necessary sensitivity and specificity to serve as an isolated screening tool 30 .

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